Sancti Spiritus, in Sancti Spiritus Province, Cuba, is home to roughly 127,000 people in the America/Havana time zone at 21.9°N latitude.
In 2025, Sancti Spiritus recorded an average annual temperature of 77°F. The hottest temperatures reached 96°F in May; the coolest were 59°F in December. Total precipitation for the year was 34 inches, with the wettest month being September.
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