About San Luis, Santiago de Cuba Province

San Luis is a city of approximately 67,300 people in Santiago de Cuba Province, Cuba. Located in the America/Havana time zone at 20.2°N latitude.

In 2025, San Luis averaged an annual temperature of 78°F, with hottest temperatures reaching 99°F in July and lowest around 59°F in December. The city received approximately 44 inches of precipitation during the year.