Santa Maria del Rio is a city of approximately 13,100 people in San Luis Potosi, Mexico. Located in the Central Time Zone at 21.8°N latitude.
In 2025, Santa Maria del Rio recorded an average annual temperature of 66°F. The hottest temperatures reached 97°F in May; the coolest were 34°F in January. Total precipitation for the year was 20 inches, with the wettest month being July.
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