With a population of around 5,300, Santa Maria Ixtulco sits in Tlaxcala, Mexico. The city operates in the Central Time Zone.
In 2025, Santa Maria Ixtulco recorded an average annual temperature of 61°F. The hottest temperatures reached 87°F in May; the coolest were 40°F in November. Total precipitation for the year was 42 inches, with the wettest month being June.
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