Carlisle, in Ohio, United States, is home to roughly 5,300 people in the Eastern Time Zone at 39.6°N latitude.
In 2025, Carlisle recorded an average annual temperature of 53°F — right at the 30-year normal of 54°F. The hottest day reached 93°F in June; the coldest was -6°F in January. Total precipitation was 46 inches (wetter than usual). The wettest month was April.
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