Santo Domingo is a city of approximately 45,500 people in Villa Clara Province, Cuba. Located in the America/Havana time zone at 22.6°N latitude.
In 2025, Santo Domingo averaged an annual temperature of 78°F, with hottest temperatures reaching 99°F in May and lowest around 57°F in December. The city received approximately 44 inches of precipitation during the year.
View historical weather for Santo Domingo · More cities in Villa Clara Province