Santo Domingo is a city of approximately 45,500 people in Villa Clara Province, Cuba. Located in the America/Havana time zone at 22.6°N latitude.
In 2025, Santo Domingo recorded an average annual temperature of 78°F. The hottest temperatures reached 99°F in May; the coolest were 57°F in December. Total precipitation for the year was 44 inches, with the wettest month being September.
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